Transcription Blockage Leads to New Beginnings

Transcription Blockage Leads to New Beginnings

Environmental agents are constantly challenging cells by damaging DNA, leading to the blockage of transcription elongation. How do cells deal with transcription-blockage and how is transcription restarted after the blocking lesions are removed? Here we review the processes responsible for the removal of transcription-blocking lesions, as well as mechanisms of transcription restart. We also disc...

New Beginnings.

Transitions in life are both inevitable and critical. Over the past 6 months, CQO has commenced an important shift as its founding editorial team has finished its remarkable term and a new group of editors takes over the journal for the next 5 years. As the incoming Editor-in-Chief for CQO’s new group of editors, I am excited and humbled by the opportunities that now lie before us. This is my f...

New beginnings.

of a wife who has spent a lot of time in Young Women, I have attended many “New Beginnings.” I have always liked the name but sometimes half jokingly say to Susan, “Why do Young Women call it ‘New Beginnings’? Why not just ‘Beginnings’? What is the diff erence between a ‘beginning’ and a ‘new beginning’?” Isn’t ‘new’ redundant?” Lately, however, I have felt new appreciation for the “new” in “Ne...

New beginnings.

How to Prevent Intra-Operatory Capsular Blockage? A New Surgical Approach: The Anti-Blockage Technique

Phacoemulsification is the technique of choice for most cataract surgeons worldwide. This technique can have complications at any of its stages, including intra or post-operative stages. The frequency of the presentation of intraoperative complications varies according to the surgeon’s experience [1], the type of cataract and whether suitable instruments are used [2]. Capsular blockage syndrome...